Brondesbury was a Roman fort guarding Watling Street. It was surrounded by woodland, which was cleared by the 17t century for cattle. The Hampstead Junction Railway line passed through Brondesbury in the 1860s, and this led to a rash of developments but mainly of fairly high-class housing for city businessmen. In the 20th century, Brondesbury Park was further developed towards Willesden Green.

This is an area of mainly 1930s houses in expansive streets. The most sought-after location is Manor House Drive, a crescent containing large detached houses. Large exclusive houses are also to be found in Christchurch Avenue, The Avenue and Aylestone Avenue. These streets also contain Victorian houses which have been converted into flats. Brondesbury Park (the road) contains blocks of flats and converted Victorian houses. Kingsbury Court and Westwood Court are recent flat developments. Honeyman Close is an enclave of smaller houses in the Arts and Crafts style.